Welcome to the Mizuguchi Laboratory

We are based in the National Institutes of Biomedical Innovation, Health and Nutrition, Japan. We carry out bioinformatics and computational biology research into drug discovery and development (with special emphasis on early-stage target discovery and toxicity prediction). Our research involves both the analysis of real-life experimental data and the development of novel computational techniques, aiming to establish systems approaches to drug discovery.

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Research Topics

2019-10-23
Research Scientist, Mari Itoh, Postdoctoral Fellow, Hitoshi Kawashima, Postdoctoral Fellow, Reiko Watanabe, Project Researcher, Takeshi Fujiwara and Tsuyoshi Esaki will give poster presentation at Chem-Bio Informatics Society(CBI).
2019-10-23
Postdoctoral Fellow, Hitoshi Kawashima and Postdoctoral Fellow, Reiko Watanabe will give poster presentation at American Association of Pharmaceutical Scientists (AAPS).
2019-10-09
Project Leader, Kenji Mizuguchi will give an invited lecture at The 4th Symposium of the Inter-University Research Network for Trans-Omics Medicine.
2019-10-02
Postdoctoral Fellow, Jonguk Park will give oral presentation at The 61st Annual Meeting of Japanese Association for Oral Biology.
2019-09-12
Project Leader, Kenji Mizuguchi will give a speech at The 14th International Symposium of the Institute Network for Biomedical Sciences.
2019-08-28
Takeshi Fujiwara will give oral presentation at the Japanese biochemical society.
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News

Research Scientist, Mari Itoh, Postdoctoral Fellow, Hitoshi Kawashima, Postdoctoral Fellow, Reiko Watanabe, Project Researcher, Takeshi Fujiwara and Tsuyoshi Esaki will give poster presentation at Chem-Bio Informatics Society(CBI).

2019-10-22 ~ 2019-10-24

Tower Hall Funabori

(4 Chome-1-1 Funabori, Edogawa City, Tokyo 134-0091)

Research Scientist, Mari Itoh, Postdoctoral Fellow, Hitoshi Kawashima, Postdoctoral Fellow, Reiko Watanabe, Project Researcher, Takeshi Fujiwara and Tsuyoshi Esaki will give poster presentation at Chem-Bio Informatics Society(CBI).

  • P5-06 (Development of a pharmacokinetics prediction system using multiscale integrated modeling: 13. Development of DruMAP, Drug Metabolism and pharmacokinetics Analysis Platform)
  • P5-07 (Development of a pharmacokinetics prediction system using multiscale integrated modeling: 14. In silico three-class predictor of human intestinal absorption with Caco-2 permeability and dried-DMSO solubility)
  • P5-08 (Development of a pharmacokinetics prediction system using multiscale integrated modeling:15. Development of an in silico prediction system of human renal excretion and clearance from chemical structure information)
  • P6-09 (Computational drug target prediction using PU learning approach)

More information is available at the following links.

2019-10-23

Postdoctoral Fellow, Hitoshi Kawashima and Postdoctoral Fellow, Reiko Watanabe will give poster presentation at American Association of Pharmaceutical Scientists (AAPS).

2019-11-03 ~ 2019-11-06

Henry B. Gonzalez Convention Center

(900 E Market St, San Antonio, TX 78205, United States)

Postdoctoral Fellow, Hitoshi Kawashima and Postdoctoral Fellow, Reiko Watanabe will give poster presentation at American Association of Pharmaceutical Scientists (AAPS).

  • Development of DruMAP, Drug Metabolism and pharmacokinetics Analysis Platform
  • Development of in silico prediction models to evaluate pharmacokinetic profiles using chemical structure information

More information is available at the following links.

2019-10-23

Project Leader, Kenji Mizuguchi will give an invited lecture at The 4th Symposium of the Inter-University Research Network for Trans-Omics Medicine.

2019-11-14 13:00 ~ 2019-11-15 16:00

Institute for Genome Research, Tokushima University

(3-18-15 Kuramotoch┼Ź, Tokushima, 770-0042)

Project Leader, Kenji Mizuguchi will give an invited lecture at The 4th Symposium of the Inter-University Research Network for Trans-Omics Medicine.

  • Artificial intelligence-based drug discovery: challenges and applications to target identification and pharmacokinetic modelling

More information is available at the following links.

2019-10-09
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