Dr.Takeshi Fujiwara and Mr. Hideyo Kamada joined our laboratory.
Poster Title： ”Development of a pharmacokinetics prediction system using multiscale integrated modeling:3. Prediction of human plasma protein binding from chemical structures”
Author: Reiko Watanabe, Tsuyoshi Esaki, Hitoshi Kawashima, Yayoi Natsume-Kitatani, Chioko Nagao, Rikiya Ohashi, Kenji Mizuguchi
Mr.Chihiro Higuchi, as Technical Assistant, and Ms Naoko Kurihara, as Collaborative Research Scientist, joined our laboratory.
April 26th, 14：30～
the seminar room@second floor of the annex, National Institute of Biomedical Innovation, Health and Nutrition
Guest Speaker: Dr. Janez Konc (Assistant Professor, Medicinal Chemistry, Faculty of Pharmacy, University of Ljubljana, Slovenia)
Seminar title：GenProBiS: Web Server for Mapping of Sequence Variants to Protein Binding Sites
Abstract: GenProBiS web server (http://genprobis.insilab.org) maps sequence variants to protein structures from the Protein Data Bank (PDB), and further to protein-protein, protein-nucleic acid, protein-compound, protein-metal ion binding sites.The server allows intuitive visual exploration of comprehensively mapped variants, such as human somatic missense mutations related to cancer and non-synonymous single nucleotide polymorphisms from several species, within the predicted binding sites regions for about 80,000 PDB protein structures using fast Molmil enabled graphics.
Thank you for attending our seminar with Dr Janez!!
Dr Rikiya Ohashi from Mitsubishi Tanabe Pharmacy as Visiting Scientist, Dr Jonguk Park as a Postdoc, and Tatsuya Kameyama and Haruka Ikuta as gratuate students.
Poster Title： ”Using gene expression profiles to identify the underlying mechanism of adverse drug events”
Author: Attayeb Mohsen, Kenji Mizuguchi
We had a seminar about “Computer Algorithm Development for Binding Site Prediction in Pharmaceutical Discovery” at University of Primorska in Slovenia. They will visit Japan and our seminar will be held at NIBIOHN next time in November.