April 26th,　14：30～

the seminar room@second floor of the annex, National Institute of Biomedical Innovation, Health and Nutrition

Guest Speaker: Dr. Janez Konc (Assistant Professor, Medicinal Chemistry, Faculty of Pharmacy, University of Ljubljana, Slovenia)

Seminar title：GenProBiS: Web Server for Mapping of Sequence Variants to Protein Binding Sites

Abstract: GenProBiS web server (http://genprobis.insilab.org) maps sequence variants to protein structures from the Protein Data Bank (PDB), and further to protein-protein, protein-nucleic acid, protein-compound, protein-metal ion binding sites.The server allows intuitive visual exploration of comprehensively mapped variants, such as human somatic missense mutations related to cancer and non-synonymous single nucleotide polymorphisms from several species, within the predicted binding sites regions for about 80,000 PDB protein structures using fast Molmil enabled graphics.

Thank you for attending our seminar with Dr Janez!!

Dr Rikiya Ohashi from Mitsubishi Tanabe Pharmacy as Visiting Scientist,  Dr Jonguk Park  as a Postdoc, and Tatsuya Kameyama and Haruka Ikuta as gratuate students.

Poster Title： ”Using gene ezpression profiles to identify the underlying mechanism of adverse drug events”

Author: Attayeb Mohsen, Kenji Mizuguchi

2016poster award winners

We had a seminar about “Computer Algorithm Development for Binding Site Prediction in Pharmaceutical Discovery” at University of Primorska in Slovenia. They will visit Japan and our seminar will be held at NIBIOHN next time in November.

University of Primorska

Seminar room

Presentation by Prof. Haruki Nakamura

Presentation by Dr. Kenji Mizuguchi

Presentation by Prof. Dusanka Janezic