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Align your sequence(s)

pyridine nucleotide-disulphide oxidoreductases class-I

class : multi domain number of structures : 11 average size : 452 average PID : 30 %

PDB
code
start
residue
start
chain
end
residue
end
chain
name source resolution R-factor
2tpr rasmol 1 A 482 A trypanothione reductase Crithidia fasciculata 2.40 18.00
1nda rasmol 4 A 484 A trypanothione reductase Crithidia cruzi 3.30 20.60
3grs rasmol 18 - 478 - glutathione reductase Homo sapiens 1.50 18.60
1ger rasmol 3 A 450 A glutathione reductase Escherichia coli 1.86 16.80
1ojt rasmol 117 - 598 - surface protein (dihydrolipoamide dehydrogenase domain) Neisseria meningitidis 2.70 17.3
1ebd rasmol 7 A 461 A dihydrolipoamide dehydrogenase Bacillus stearothermophilus 2.60 21.5
3lad rasmol 1 A 472 A lipoamide dehydrogenase Azotobacter vinelandii 2.20 19.80
1lpf rasmol 1 A 472 A lipoamide dehydrogenase Pseudomonas fluorescens 2.80 19.60
1lvl rasmol 1 - 458 - lipoamide dehydrogenase Pseudomonas putida 2.45 21.50
1npx rasmol 1 - 447 - NADH peroxidase Streptococcus faecalis 2.20 17.70
1trb rasmol 1 - 316 - thioredoxin reductase Escherichia coli 2.0 17.7
pir | ali | malform | joy-html | colour postscript | postscript | superimposed coordinates (RasMol)

external links
PFAM : pyr_redox_dim  pyr_redox  
other info key to JOY annotation | show related PDB structures

                           10        20        30        40        50  
2tpra  (   1 )       sraYdLVVIGAGsGGleAGwnAAslh-kkrVAVIDLqkhhGpphyAA
1ndaa  (   4 )         iFdLVVIGAGsGGLeAAwnAAtly-kkrVAVIDVqmvhGppffSA
3grs   (  18 )       vasydYLVIGGGsGGLaSArrAael--gArAAVVEsh---------k
1gera  (   3 )        khYdYIAIGGGsGGiaSInrAAmy--gqkCALIEak---------e
1ojt   ( 117 )    gsadaeYdVVVLGGGPGGysAAfaAAde--glkVAIVEryk--------t
1ebda  (   7 )       aieteTLVVGAGpGGyvAAirAaql--gqkVTIVEkg---------n
3lada  (   1 )       sqkFdVIVIGAGpGGyvAAikSAql--glkTALIEkykGk--egkta
1lpfa  (   1 )       sqkFdVVVIGAGpGGyvAAirAAql--glkTACIEkyaGk--agatA
1lvl   (   1 )     qqtiqttLLIIGGGPGGyvAAirAgql--gipTVLVEGq---------a
1npx   (   1 )          mkVIVLGSsHGGyeAVeELlnlhpdAeIqWYEkg--------df
1trb   (   1 )     gttkhskLLILGSGPAGYtAAvyAAra--nlqPVLITGm---------e
                       b  bbbb   aaaaaaaaaaaa      bbbbb            

                           60        70        80        90        100 
2tpra  (  47 )    LGGTçvNVGçvPKklMVtgAnymDtir-esa--gfgweldresvrpnWka
1ndaa  (  48 )    LGGTçvNVGçvPKklMvtgAqymEhlr-esa--gfgwefdrttlraeWkk
3grs   (  54 )    lGGtçVnvGçvPKkvMwntAvhsefmh-Dha--dygfpsce--gkfnWrv
1gera  (  38 )    lGGtçVnvGçvPKkvMwhaAqireaihmYgp--dygfdtti--nkfnwet
1ojt   ( 157 )    LGGvçLNvGçiPSkaLLhnAavidevrh-la--angikyp--epeldidm
1ebda  (  43 )    lGGvçlnvGçiPSkaLisaShryeqakh-se--emgikae--nvtidFak
3lada  (  44 )    LGGtçlNvGçiPSkaLLdsSykfheahesfk--lhgistg--evaidVpt
1lpfa  (  44 )    lGGtçlNvGçiPSkaLLdsSykyheaaeafk--vhgieaa--gvtidvpa
1lvl   (  39 )    lGGTçLniGçiPSkaLihvAeqfhqasrftepsplgisva--sprldIgq
1npx   (  37 )    ISFl----scgMqlYLegkvk-----------------------------
1trb   (  39 )    kgGQLttTt--eVenwpgdpn-----------------------------
                    aaaaa  aaaaaaaaaaaaaaaaaa   3  33            aaa

                           110       120       130       140       150 
2tpra  (  94 )    liaaKnkaVsgiNdsyegmfadTegLtfhq-gfGALq-dn-h--tVlVre
1ndaa  (  95 )    liavKdeaVlniNksyeemFrdtegLeffl-gwGSLe-sk-n--vVNVre
3grs   (  99 )    ikekRdayvsrlnaiyqnnLtksh-IeIir-ghAaFtsdpkp--TIeVs-
1gera  (  84 )    liasRtayidrihtsyenvLgknn-Vdvik-gfArFv-da-k--tLeVn-
1ojt   ( 202 )    lraykdgvvsrlTgglagmAksrk-Vdviq-GdGqFl-dp-h--hLeVsl
1ebda  (  88 )    vqewkasvvkkltggVeglLkgnk-Veivk-geAyFv-da-n--tVrVvn
3lada  (  90 )    MiarKdqiVrnltggVaslIkang-Vtlfe-ghGkLl--agk--kVeVta
1lpfa  (  90 )    MVarkanivknltggiatlFkang-Vtsfe-GhGkLl--ank--qVeVtg
1lvl   (  87 )    svawKdgivdrlttgvaalLkkhg-Vkvvh-gwAkVl-dG-k--qVeVd-
1npx   (  54 )    -------dvnsvrymtgekMesrg-VnVfsnTeItaIqpkeh--qVtVkd
1trb   (  58 )    -----dLtGplLMermhehAtkfe-TeIif-dhInkVdLqnrpFrLnGd-
                  aaaaaaaaaaaaaaaaaaaaaa    bbbb   bbb        bbbb  

                           160       170       180       190       200 
2tpra  ( 139 )    sadpnsa------vletLdTeyILLATGSwPqhlg---iegd--dlCiT-
1ndaa  ( 140 )    sadpasa------vkerLeTenILLASGSwPhmpn---ipgi--ehCis-
3grs   ( 144 )    --------------gkkytAphILIATGGmpstphesqipgA--slGit-
1gera  ( 127 )    --------------getItAdhILIATGGrpshpd---ipgv--eyGid-
1ojt   ( 246 )    TagdayeqAaptgekkiVaFknCIIAAGSrvtklpfiped----prIid-
1ebda  ( 132 )    -----------gdsaqtYtFknAIIATGSrpielpnFkfs----nrild-
3lada  ( 134 )    a----------dgssqvLdTenVILASGSkpveippApvdq---dvIVd-
1lpfa  ( 134 )    l----------dgatqvLeAenVIIASGSapveippApltd---diIvd-
1lvl   ( 130 )    --------------gqrIqCehLLLATGSssvelpmLplg----gpVis-
1npx   (  94 )    lvsg---------eervenYdkLIISPGAvpfeld---ipgkdldnIylM
1trb   ( 100 )    --------------ngeYtCdALIIATGAsArylglpsEeafkgrGVsAc
                                 bbbb  bbbb   bbb                   

                           210       220       230       240       250 
2tpra  ( 177 )    --SneAFyld-----eaPkrALCVgGgyiSIEFAgIFNAykargGqVDLA
1ndaa  ( 178 )    --SNeAFylp-----epprrVLTVGGgfiSVEFAgIFnAykpkdGqVTLC
3grs   ( 177 )    --SdgFFqle-----elpgrSVIvgAgyiAVEMAgILsaL---gSkTSLM
1gera  ( 157 )    --SdgFFalp-----alperVAVVgagyiAVELAgVIngL---gAkThLF
1ojt   ( 291 )    --ssgALaLk-----evPgkLLIigGgiiGLEMGTVYsTL---gSrLDVV
1ebda  ( 166 )    --StgALnlg-----evPksLVVigGgyiGIELGTAYANF---gTkVtIL
3lada  ( 170 )    --StgALdFq-----nvpgkLGVigAgviGLELGSVWARL---gAeVtVL
1lpfa  ( 170 )    --StgALefq-----avPkkLGVigAgviGLELGSVWarL---gAeVTVL
1lvl   ( 161 )    --SteALaPk-----alPqhLVVVGGgyIGLELGIAYrKL---gAqVSVV
1npx   ( 132 )    rgrqwAikLkqktvdpeVnnVVVIgSgyiGIEAAEAFAka---gkkVtVI
1trb   ( 136 )    AtSdGffyrnq--------kVAVigGGntAVeeALyLSniAs---eVhLI
                    aaaa             bbbbb   aaaaaaaaaaaa      bbbbb

                           260       270       280       290       300 
2tpra  ( 220 )    yrgdmILrg-fDseLRkqLteQLrangInVrthenPakVtknadgtrhVv
1ndaa  ( 221 )    YrgemILrg-fDhtLreeLtkQLtangIqIltkenPakVelnadgSkSVt
3grs   ( 217 )    IrhdkVLrs-fDsmIStnCTeelenagVeVlkfSqVkeVkktl-sgleVs
1gera  ( 197 )    VrkhAPLrs-fDpmIseTLveVMnaegPqLhtnAipkaVvkntdgsLtLe
1ojt   ( 331 )    emmdgLMqg-ADrdLVkvWqkqNeyRFdniMvnTkTvaVepke-dgVyVt
1ebda  ( 206 )    egageILsg-fEkqMAaiIkkrLkkkgVeVvtnAlakgAeere-dGVtVt
3lada  ( 210 )    eamdkFlpa-vDeqVakeAqkiLtkqgLkIllgArVtgtevkn-kqVtVk
1lpfa  ( 210 )    ealdkFlpa-ADeqIakeAlkvLtkqgLnIrlgArVtaSevkk-kqVtVt
1lvl   ( 201 )    EarerILPt-ydseLTapVaesLkklgIalhlghsVegyen-----gcLl
1npx   ( 179 )    dildrPLgvyLDkeFTdvLteeMeannItIatgetVerYegd-grVqkVv
1trb   ( 175 )    hrrdgF---rAekilikrLmdkvengnIilhtnrtLeeVtGdqmgVtgVr
                              aaaaaaaaaaaaa   bbb    bbbbbb     bbbb

                           310       320       330       340       350 
2tpra  ( 269 )    Fes--------gaead-YdvVMLaigrvPrSqtLqLekAgVevakngaIk
1ndaa  ( 270 )    Fes--------gkkmd-FdlVMMaigrsPRtkdLqLqnAgVmikn-gGVq
3grs   ( 265 )    MvtavpgrlpvmtmipdVdcLLWaigrvPnTkdLslnklgIqtddkghIi
1gera  ( 246 )    Led--------grset-VdcLIWaigrePaNdnInLeaAgVktnekgyIv
1ojt   ( 379 )    Fega----nApkepqr-YdaVLvaagraPNGklIsAekAgVavtdrgfIe
1ebda  ( 254 )    Yean----get-ktid-AdyVLVtvgrrpnTdeLGLeqigIkmtnrglIe
3lada  ( 258 )    Fvda----ege-ksqa-FdkLIVavgrrPvttdLlaadSgVtldergfIy
1lpfa  ( 258 )    Ftda----nge-qaat-FdkLIVavgrrPvttdLlaadSgVtldergfIy
1lvl   ( 245 )    Andg----kggqlrle-AdrVLVaVgRrPrtkgFnLecLdLkmng-aAIa
1npx   ( 228 )    Tdk---------nayd-AdLVVVavgvrpnTawLk---gtLelhpngLIk
1trb   ( 222 )    Lrdtq---nsdniesldVaGLFVAighspnTaiFe---gqLelen-gyIk
                  b            bbb b bbbb   bbb                     

                           360       370       380       390       400 
2tpra  ( 310 )    Vd-----aySkTnvdnIYAIGDVTdr----------vmltpvAinEGaAF
1ndaa  ( 310 )    Vd-----eysrTnvsnIyAIGDVTnr----------vmltpVAinEAaAL
3grs   ( 315 )    vd-----efQnTnvkgIYAVgDVCGk----------alltpvAiaAGrkL
1gera  ( 287 )    vd-----kyQnTniegIYAVgDNTga----------veltpVAvaAGrrL
1ojt   ( 424 )    Vd-----kqMrTnvphIYAIGDIvgq----------pMlahKAvhEGhvA
1ebda  ( 298 )    vd-----qqCrTsvpnIFAIGDIVpg----------palahKAsyEGkvA
3lada  ( 302 )    Vd-----dyCaTsvpgVYAIGDVVrg----------amlahKAseEGvvV
1lpfa  ( 302 )    Vd-----dhCkTsvpgVfAIGDVVrg----------amlahKAseEGvMV
1lvl   ( 289 )    id-----erCqTsmhnVWAIGDVAge----------pMlahRAmaQGeMV
1npx   ( 265 )    Td-----eyMrTsepdVFAVGDATlIkYnPadteVnialatnArkQGrfA
1trb   ( 265 )    vqsgihgnaTqTsipGVFAAGDVmdhi---------yrqAitSagtGcmA
                                  bbb 333                aaaaaaaaaaa

                           410       420       430       440       450 
2tpra  ( 345 )    VdtVFa---nk-praTdhtkvacaVfSi-PpMGvCgyveedAAkky--dq
1ndaa  ( 345 )    Vdtvfg---tn-prkTdhtrvasaVfSi-PpIGtCgliEevAskry--ev
3grs   ( 350 )    Ahrlfe---ykedskldynniptvVfSh-PPIGtVgltedeAihkygien
1gera  ( 322 )    SerlFn---nkpdehldysniptvVfSh-PPIGtVgltepqAreqygddq
1ojt   ( 459 )    AeNCag-----hkayfdarVipgVAyTs-PeVAwVgetelsAkasa----
1ebda  ( 333 )    AeAIag-----hpsavdyvaipavVfSD-PeCASVgyfeqqAkdeg----
3lada  ( 337 )    AerIag-----hkaqmnydlipavIyTh-peIAgVgkteqaLkaeg----
1lpfa  ( 337 )    Aeriag-----hkaqmnydlipsvIyTh-PeIAwVgkteqtLkaeg----
1lvl   ( 324 )    AeiIag-----karrfepaaiaavCfTd-PeVVvVgkTpeqAsqqg----
1npx   ( 310 )    VkNLe-----epvkpFpGvQgssglaVfdykFAsTGINevmaqklgk--e
1trb   ( 306 )    AlDAeryldgl                                       
                  aaaa                  bbb      bbbbb  aaaaaa      

                           460       470       480       490       500 
2tpra  ( 388 )    VAVYessftp---lmhniSgStykkFmVRIVTnhadgeVLGVHMLg-dsS
1ndaa  ( 388 )    VAVYlssftp---lmHniSgSkyKtFVAKIITnhsdgtVLGVHLLg-dnA
3grs   ( 396 )    VktystsftP---myHavTkrk-tkCvMkMVCAnkeekVvGIHMQG-lgC
1gera  ( 368 )    VkVykssfta---myTavTthr-QpCrMKLVCvgseekIvGIHGIG-fgM
1ojt   ( 499 )    rkitkAnFpWaasgrAiangCd--kPfTKLIFdaetgrIIGGGIVG-pnG
1ebda  ( 373 )    idViaAkfpFaangrAlalndt--dGfLKLVVrkedgvIiGAQIIG-pnA
3lada  ( 377 )    vainvGvFpFaasgrAmaandt--aGfVKVIAdaktdrVlGVHVIG-psA
1lpfa  ( 377 )    veVnvGtFpFttsgrAmaandt--tGlVKVIAdaktdrVlGVHVIG-psA
1lvl   ( 364 )    ldcivaqFpFaaNgrAmslesk--sgfVRVVArrdnhlIlGWQAVG-vaV
1npx   ( 353 )    tkavtvvedyLmdfnp-----dkqkAwFkLVYdpettqIlGAQLMSkadl
1trb                                                                
                    bbbbbb     aaaa         bbbbbbb     bbbbbbb    a

                           510       520       530       540       550 
2tpra  ( 434 )    peiIqsvaicLkmgakisdvynt--igvhpt--saeelcsmrtpa---yf
1ndaa  ( 434 )    peiIqgvgicLklnakisdFynt--igvhpt--saeelcsmrtPs---yy
3grs   ( 441 )    demLqgfAvaVkmgatKadFdnt--vaihpt--sseeLvtLr        
1gera  ( 413 )    demLqgfAvaLkmgatkkdFdnt--vaihpt--aaeeFvtMr        
1ojt   ( 546 )    GdmIgeVclaIemgcdaadIGkt--ihphpt--lgeSIgmAAevalg-tC
1ebda  ( 420 )    sdmIaeLglAIeagmtAedIAlt--ihahpt--LgeIAmeAAevAl    
3lada  ( 424 )    aeLVqqGaiamefgTsAedLGmm--vfahpa--lseALheAAlaVsg-hA
1lpfa  ( 424 )    aeLVqqGaigmefgtsAedLGmm--vfshpt--lseALheAAlaVng-hA
1lvl   ( 411 )    selstaFaqsLemgacLedvAgt--ihahpt--lgeAvqeAAlrAlg-hA
1npx   ( 398 )    tanInaIslAIqakmtIedLAyadfffqpafdkpwniINtAAleAvkqer
1trb                                                                
                  aaaaaaaaaaaa    aaaaa                             

                          
2tpra  ( 477 )    yekgkr  
1ndaa  ( 477 )    yvkgekme
3grs                      
1gera                     
1ojt   ( 591 )    tdlppqkk
1ebda                     
3lada  ( 469 )    ihva    
1lpfa  ( 469 )    ihia    
1lvl   ( 456 )    lhi     
1npx                      
1trb                      
                          


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