Development of a novel method for modelling dynamic structures of membrane proteins

Summary
We aim to combine bioinformatic and molecular simulation techniques (by our collaborators) to develop a novel method for modelling the dynamic structure of membrane proteins. See a Japanese summary on the JST website.

Funding
Institute of Bioinformatics Research and Development, Japan Science and Technology Agency (JST-BIRD), Japan (2007-2010) “Development of a method for modelling dynamic structures of membrane proteins ” (Principal Investigator: Kenji Mizuguchi)

Recent achievements
HTM-ONE server
MultiCoMP database

Reference
Ahmad S., Singh YH., Paudel Y., Mori T., Sugita Y., Mizuguchi K., Integrated prediction of one-dimensional structural features and their relationships with conformational flexibility in helical membrane proteins, BMC Bioinformatics, 11:533, 2010 PubMed

Collaborators:
Yuji Sugita(Riken),Yuko Okamoto(Nagoya University),Hiroyuki Mori (Kyoto University)